Glossary
ALLOGENEIC DONATION
Blood and blood components collected from an individual and intended for transfusion to another individual, for use in medical devices or as source material for manufacturing into medicinal products.
ANTIBODIES
Natural proteins made by the immune system of the body. They are needed to stop some infections.
APHERESIS
Pronounced ay-fur-ee-sis, it comes from the Greek word meaning “to take away” or “to separate”. It is a method of obtaining one or more blood components by machine processing of whole blood in which the residual components of the blood are returned to the donor during or at the end of the process.
AUTOLOGOUS DONATION
Blood and blood components collected from an individual, intended solely for subsequent autologous transfusion to the individual.
BLOOD
Whole blood collected from a single donor and processed either for transfusion or further manufacturing.
BLOOD BANK
Blood Banks are laboratories within the hospital that store and distribute blood products to clinical departments in local hospitals. They also test a sample of the patient’s blood to ensure the donor’s blood product is compatible.
BLOOD COMPONENT
Therapeutic components of blood (red cells, white cells, platelets, plasma) that can be prepared by centrifugation, filtration, and freezing using conventional blood bank methodology.
BLOOD TRANSFUSION
A treatment arranged by a doctor which involves giving blood or a product made from blood, to a patient.
CREUTZFELDT-JAKOB DISEASE (CJD)
A rare disease that affects the brain and causes severe mental failure, dementia and eventually death.
CRYOPRECIPITATE
Plasma component prepared from fresh frozen plasma by freeze-thaw precipitation of proteins and subsequent concentration and resuspension of the precipitated proteins in a small volume of plasma.
DEFERRAL
Suspension of the eligibility of an individual to donate blood or blood components, such suspension being either permanent or temporary.
FRESH FROZEN PLASMA
A component prepared from whole blood or from plasma collected by apheresis frozen to a temperature that will maintain the labile coagulation factors in a functional state.
HAEMOCHROMATOSIS
An inherited condition that causes a build up of very large amounts of iron in the body.
HAEMOVIGILANCE
Organised surveillance procedures related to severe adverse or unexpected events or reactions in donors or recipients, and the epidemiological follow up of donors.
HIV
Human Immunodeficiency Virus (HIV) is the virus that leads to the range of infections called Acquired Immune Deficiency Syndrome (AIDS).
PLASMAPHERESIS
Process of collecting plasma with an apheresis machine. As the blood is taken from the donor, the machine spins the blood to separate the plasma from the other blood components. The plasma is collected into a special collection bag and the remaining red cells, white cells and platelets are returned back to the donor.
PLATELETPHERESIS
Plateletpheresis is the process of collecting platelets with an apheresis machine. As blood is taken from the donor, the machine spins the blood in a small centrifuge bowl to separate the platelets from the other blood components. These are collected into a special collection bag and the remaining red cells, white cells and most of the plasma are then returned to the donor.
RED BLOOD CELLS
The blood cells that carry oxygen. Red cells contain haemoglobin and it is the haemoglobin that permits them to transport oxygen (and carbon dioxide).
RED CELL COMPONENT
A component obtained from a single whole blood donation by removal of part of the plasma, without further processing.
RH
A blood group on red blood cells of some people, also called the Rhesus factor. If you do not have the Rh factor, you are Rh (D) negative.
RH D IMMUNOGLOBULIN
Immunoglobulin specific for Rh D antigen is given routinely to Rh (D) negative mothers bearing Rh (D) positive infants to protect them from red cell exposure during pregnancy and delivery, and so prevent alloimmunisation.
VARIANT CJD (VCJD)
A new disease believed to be the human form of Bovine Spongiform Encephalopathy (BSE), a disease that affected cattle.